In IT we trust: IT can hack happiness, can IT create happiness too?

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C2 Can Do It, Too

In this issue of Cell, report that the C2 domain of the serine/threonine protein kinase Cdelta is a phosphotyrosine binding domain and present the crystal structure of this C2 domain bound to a peptide containing phosphotyrosine. Prior to this work, C2 domains were thought to bind only to phospholipids or to unphosphorylated proteins, and the SH2 and PTB domains were the only signaling domains ...

We can make it happen

No abstract available.

Adaptive developmental plasticity: what is it, how can we recognize it and when can it evolve?

Developmental plasticity describes situations where a specific input during an individual's development produces a lasting alteration in phenotype. Some instances of developmental plasticity may be adaptive, meaning that the tendency to produce the phenotype conditional on having experienced the developmental input has been under positive selection. We discuss the necessary assumptions and pred...

Trustworthy Software: Why we need it, Why we don't have it, How we can get it

We have become increasingly dependent on a national technological fabric that contains software, computers, and communication networks as essential components. Unfortunately, our ability to build affordable software systems for which there exists compelling evidence that the systems delivers their services in a manner that satisfies certain critical properties has not kept pace with the importa...